{"id":2974,"date":"2026-10-13T18:32:33","date_gmt":"2026-10-13T18:32:33","guid":{"rendered":"https:\/\/videoteca.svpediatria.org\/?page_id=2974"},"modified":"2026-10-14T16:56:26","modified_gmt":"2026-10-14T16:56:26","slug":"cardiologia","status":"publish","type":"page","link":"https:\/\/videoteca.svpediatria.org\/?page_id=2974","title":{"rendered":"Cardiolog\u00eda"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"2974\" class=\"elementor elementor-2974\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9f6ae7e e-grid e-con-boxed e-con e-parent\" data-id=\"9f6ae7e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b2dd6ae e-grid e-con-full e-con e-child\" data-id=\"b2dd6ae\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-cdd7a76 e-con-full e-flex e-con e-child\" data-id=\"cdd7a76\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-88e3cef e-grid e-con-full e-con e-child\" data-id=\"88e3cef\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e3da498 elementor-widget elementor-widget-image\" data-id=\"e3da498\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/videoteca.svpediatria.org\/?page_id=624\">\n\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"171\" src=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/08\/1-300x171.jpg\" class=\"attachment-medium size-medium wp-image-704\" alt=\"\" srcset=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/08\/1-300x171.jpg 300w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/08\/1.jpg 700w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c6c2849 e-grid e-con-boxed e-con e-parent\" data-id=\"c6c2849\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7b07051 e-grid e-con-full e-con e-child\" data-id=\"7b07051\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-7bc5bb4 e-con-full e-flex e-con e-child\" data-id=\"7bc5bb4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-d69aec0 e-grid e-con-full e-con e-child\" data-id=\"d69aec0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-47602b1 e-grid e-con-full e-con e-child\" data-id=\"47602b1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6fa15ea elementor-widget elementor-widget-text-editor\" data-id=\"6fa15ea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h1 style=\"text-align: center;\"><img decoding=\"async\" class=\"wp-image-761  aligncenter\" src=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/Cardio-300x250.png\" alt=\"\" width=\"168\" height=\"140\" srcset=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/Cardio-300x250.png 300w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/Cardio-1024x853.png 1024w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/Cardio-768x640.png 768w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/Cardio-1536x1279.png 1536w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/Cardio-2048x1706.png 2048w\" sizes=\"(max-width: 168px) 100vw, 168px\" \/><span style=\"color: #68c4e3;\">Cardiolog\u00eda<\/span><\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-588f3c4 e-grid e-con-boxed e-con e-parent\" data-id=\"588f3c4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2b2ff0e e-con-full e-flex e-con e-child\" data-id=\"2b2ff0e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-5e6e9f5 e-grid e-con-full e-con e-child\" data-id=\"5e6e9f5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-85495cd e-con-full e-flex e-con e-child\" data-id=\"85495cd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-d35b095 e-con-full e-flex e-con e-child\" data-id=\"d35b095\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-9bfb8d5 e-con-full e-flex e-con e-child\" data-id=\"9bfb8d5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-598e2aa elementor-widget elementor-widget-n-accordion\" data-id=\"598e2aa\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-9390\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-9390\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> Diagn\u00f3stico, manejo y tratamiento de la enfermedad de Kawasaki <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-file-medical\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M377 105L279.1 7c-4.5-4.5-10.6-7-17-7H256v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm64 160v48c0 4.4-3.6 8-8 8h-56v56c0 4.4-3.6 8-8 8h-48c-4.4 0-8-3.6-8-8v-56h-56c-4.4 0-8-3.6-8-8v-48c0-4.4 3.6-8 8-8h56v-56c0-4.4 3.6-8 8-8h48c4.4 0 8 3.6 8 8v56h56c4.4 0 8 3.6 8 8z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-65511d5 e-con-full e-flex e-con e-child\" data-id=\"65511d5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-3d5401b e-flex e-con-boxed e-con e-child\" data-id=\"3d5401b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a7d9f24 elementor-widget elementor-widget-image\" data-id=\"a7d9f24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki.jpg\" data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-title=\"EnfermedadKawasaki\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MzA2MywidXJsIjoiaHR0cHM6XC9cL3ZpZGVvdGVjYS5zdnBlZGlhdHJpYS5vcmdcL3dwLWNvbnRlbnRcL3VwbG9hZHNcLzIwMjZcLzEwXC9FbmZlcm1lZGFkS2F3YXNha2kuanBnIn0%3D\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"634\" height=\"1024\" src=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki-634x1024.jpg\" class=\"attachment-large size-large wp-image-3063\" alt=\"\" srcset=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki-634x1024.jpg 634w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki-186x300.jpg 186w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki-768x1241.jpg 768w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki-951x1536.jpg 951w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki-1268x2048.jpg 1268w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EnfermedadKawasaki.jpg 1300w\" sizes=\"(max-width: 634px) 100vw, 634px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\"><\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-8297d1d e-con-full e-grid e-con e-child\" data-id=\"8297d1d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7bd580f e-n-tabs-mobile elementor-widget elementor-widget-n-tabs\" data-id=\"7bd580f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;horizontal_scroll&quot;:&quot;disable&quot;}\" data-widget_type=\"nested-tabs.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-tabs\" data-widget-number=\"129849359\" aria-label=\"Pesta\u00f1as. 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abreviaturas\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-12984935914\" data-tab-title-id=\"e-n-tab-title-12984935914\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"14\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-12984935914\" style=\"--n-tabs-title-order: 14;\">\n\t\t\t\t\t<span class=\"e-n-tab-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-user-edit\" viewBox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224 256c70.7 0 128-57.3 128-128S294.7 0 224 0 96 57.3 96 128s57.3 128 128 128zm89.6 32h-16.7c-22.2 10.2-46.9 16-72.9 16s-50.6-5.8-72.9-16h-16.7C60.2 288 0 348.2 0 422.4V464c0 26.5 21.5 48 48 48h274.9c-2.4-6.8-3.4-14-2.6-21.3l6.8-60.9 1.2-11.1 7.9-7.9 77.3-77.3c-24.5-27.7-60-45.5-99.9-45.5zm45.3 145.3l-6.8 61c-1.1 10.2 7.5 18.8 17.6 17.6l60.9-6.8 137.9-137.9-71.7-71.7-137.9 137.8zM633 268.9L595.1 231c-9.3-9.3-24.5-9.3-33.8 0l-37.8 37.8-4.1 4.1 71.8 71.7 41.8-41.8c9.3-9.4 9.3-24.5 0-33.9z\"><\/path><\/svg>\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-user-edit\" viewBox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224 256c70.7 0 128-57.3 128-128S294.7 0 224 0 96 57.3 96 128s57.3 128 128 128zm89.6 32h-16.7c-22.2 10.2-46.9 16-72.9 16s-50.6-5.8-72.9-16h-16.7C60.2 288 0 348.2 0 422.4V464c0 26.5 21.5 48 48 48h274.9c-2.4-6.8-3.4-14-2.6-21.3l6.8-60.9 1.2-11.1 7.9-7.9 77.3-77.3c-24.5-27.7-60-45.5-99.9-45.5zm45.3 145.3l-6.8 61c-1.1 10.2 7.5 18.8 17.6 17.6l60.9-6.8 137.9-137.9-71.7-71.7-137.9 137.8zM633 268.9L595.1 231c-9.3-9.3-24.5-9.3-33.8 0l-37.8 37.8-4.1 4.1 71.8 71.7 41.8-41.8c9.3-9.4 9.3-24.5 0-33.9z\"><\/path><\/svg>\t\t<\/span>\n\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tAutores\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-12984935915\" data-tab-title-id=\"e-n-tab-title-12984935915\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"15\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-12984935915\" style=\"--n-tabs-title-order: 15;\">\n\t\t\t\t\t<span class=\"e-n-tab-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-book\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M448 360V24c0-13.3-10.7-24-24-24H96C43 0 0 43 0 96v320c0 53 43 96 96 96h328c13.3 0 24-10.7 24-24v-16c0-7.5-3.5-14.3-8.9-18.7-4.2-15.4-4.2-59.3 0-74.7 5.4-4.3 8.9-11.1 8.9-18.6zM128 134c0-3.3 2.7-6 6-6h212c3.3 0 6 2.7 6 6v20c0 3.3-2.7 6-6 6H134c-3.3 0-6-2.7-6-6v-20zm0 64c0-3.3 2.7-6 6-6h212c3.3 0 6 2.7 6 6v20c0 3.3-2.7 6-6 6H134c-3.3 0-6-2.7-6-6v-20zm253.4 250H96c-17.7 0-32-14.3-32-32 0-17.6 14.4-32 32-32h285.4c-1.9 17.1-1.9 46.9 0 64z\"><\/path><\/svg>\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-book\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M448 360V24c0-13.3-10.7-24-24-24H96C43 0 0 43 0 96v320c0 53 43 96 96 96h328c13.3 0 24-10.7 24-24v-16c0-7.5-3.5-14.3-8.9-18.7-4.2-15.4-4.2-59.3 0-74.7 5.4-4.3 8.9-11.1 8.9-18.6zM128 134c0-3.3 2.7-6 6-6h212c3.3 0 6 2.7 6 6v20c0 3.3-2.7 6-6 6H134c-3.3 0-6-2.7-6-6v-20zm0 64c0-3.3 2.7-6 6-6h212c3.3 0 6 2.7 6 6v20c0 3.3-2.7 6-6 6H134c-3.3 0-6-2.7-6-6v-20zm253.4 250H96c-17.7 0-32-14.3-32-32 0-17.6 14.4-32 32-32h285.4c-1.9 17.1-1.9 46.9 0 64z\"><\/path><\/svg>\t\t<\/span>\n\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tBibliograf\u00eda\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-12984935916\" data-tab-title-id=\"e-n-tab-title-12984935916\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"16\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-12984935916\" style=\"--n-tabs-title-order: 16;\">\n\t\t\t\t\t<span class=\"e-n-tab-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-file-download\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224 136V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm76.45 211.36l-96.42 95.7c-6.65 6.61-17.39 6.61-24.04 0l-96.42-95.7C73.42 337.29 80.54 320 94.82 320H160v-80c0-8.84 7.16-16 16-16h32c8.84 0 16 7.16 16 16v80h65.18c14.28 0 21.4 17.29 11.27 27.36zM377 105L279.1 7c-4.5-4.5-10.6-7-17-7H256v128h128v-6.1c0-6.3-2.5-12.4-7-16.9z\"><\/path><\/svg>\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-file-download\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224 136V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm76.45 211.36l-96.42 95.7c-6.65 6.61-17.39 6.61-24.04 0l-96.42-95.7C73.42 337.29 80.54 320 94.82 320H160v-80c0-8.84 7.16-16 16-16h32c8.84 0 16 7.16 16 16v80h65.18c14.28 0 21.4 17.29 11.27 27.36zM377 105L279.1 7c-4.5-4.5-10.6-7-17-7H256v128h128v-6.1c0-6.3-2.5-12.4-7-16.9z\"><\/path><\/svg>\t\t<\/span>\n\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tDescargar Gu\u00eda\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493591\" id=\"e-n-tab-content-1298493591\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-0335809 e-con-full e-grid e-con e-child\" data-id=\"0335809\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-ff61536 e-con-full e-flex e-con e-child\" data-id=\"ff61536\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-aec01d2 e-con-full e-flex e-con e-child\" data-id=\"aec01d2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-76686ff elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"76686ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>A. Sospecha cl\u00ednica inicial y desaf\u00edos epidemiol\u00f3gicos en Venezuela\u00a0<\/b><\/span><\/p><p>En Venezuela, el diagn\u00f3stico oportuno de la Enfermedad de Kawasaki enfrenta retos epidemiol\u00f3gicos singulares. La coexistencia end\u00e9mica de infecciones arbovirales (dengue, chikungunya, zika), cuadros exantem\u00e1ticos infecciosos (sarampi\u00f3n, rub\u00e9ola, parvovirus B19) y sepsis bacterianas genera con frecuencia solapamiento de signos cl\u00ednicos o diagn\u00f3sticos tard\u00edos. La dispersi\u00f3n territorial y la variabilidad en la disponibilidad inmediata de pruebas de alta complejidad exigen consolidar un criterio cl\u00ednico-anal\u00edtico s\u00f3lido.<\/p><p>\u00a0<\/p><ul><li><strong>Alerta Pedi\u00e1trica:<\/strong> Todo lactante menor de 1 a\u00f1o con s\u00edndrome febril inexplicable de 5 o m\u00e1s d\u00edas de duraci\u00f3n debe ser evaluado rigurosamente para descartar Kawasaki Incompleto, incluso ante la ausencia de la totalidad de signos exantem\u00e1ticos o mucosos cl\u00e1sicos.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493592\" id=\"e-n-tab-content-1298493592\" data-tab-index=\"2\" style=\"--n-tabs-title-order: 2;\" class=\" elementor-element elementor-element-dec1278 e-grid e-con-boxed e-con e-child\" data-id=\"dec1278\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-68bf4dd e-con-full e-flex e-con e-child\" data-id=\"68bf4dd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cdc7f1d elementor-widget elementor-widget-text-editor\" data-id=\"cdc7f1d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>B. Kawasaki cl\u00e1sico (criterios AHA\/SVPP)<\/b><\/span><\/p><p>Fiebre persistente \u2265 5 d\u00edas (criterio cardinal obligatorio) sumada a al menos 4 de los siguientes 5 signos cl\u00ednicos:<\/p><p>\u00a0<\/p><ol><li><strong>Inyecci\u00f3n conjuntival bilateral:<\/strong> Bulbar, no exudativa, sin dolor ni supuraci\u00f3n ocular.<\/li><li><strong>Cambios labiales y orofar\u00edngeos:<\/strong> Eritema marcado, queilitis fisurada sangrante, eritema far\u00edngeo difuso, lengua en frambuesa.<\/li><li><strong>Exantema polimorfo:<\/strong> Troncal o generalizado, maculopapular, eritematoso difuso o escarlatiniforme; sin ves\u00edculas ni costras.<\/li><li><strong>Cambios en extremidades:<\/strong> Fase aguda con eritema de palmas\/plantas y edema indurado de manos\/pies; fase subaguda con descamaci\u00f3n periungueal laminar.<\/li><li><strong>Linfadenopat\u00eda cervical aguda:<\/strong> Generalmente unilateral, di\u00e1metro \u2265 1,5 cm, dolorosa, no fluctuante.<\/li><\/ol><p><strong>Punto cr\u00edtico:<\/strong> Ante confirmaci\u00f3n cl\u00ednica, iniciar de inmediato IGIV y AAS sin diferir por la realizaci\u00f3n del ecocardiograma (Nivel 1++, Grado A).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493593\" id=\"e-n-tab-content-1298493593\" data-tab-index=\"3\" style=\"--n-tabs-title-order: 3;\" class=\" elementor-element elementor-element-3a5ac45 e-grid e-con-boxed e-con e-child\" data-id=\"3a5ac45\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-d915643 e-con-full e-flex e-con e-child\" data-id=\"d915643\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7236c8f elementor-widget elementor-widget-text-editor\" data-id=\"7236c8f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>C. Kawasaki incompleto (At\u00edpico)<\/b><\/span><\/p><p>Frecuente en lactantes &lt; 12 meses y escolares &gt; 5 a\u00f1os. Se sospecha con fiebre \u2265 5 d\u00edas y 2 o 3 criterios cl\u00ednicos compatibles:<\/p><p>\u00a0<\/p><ol><li><strong>Reactantes inflamatorios elevados:<\/strong> PCR \u2265 3,0 mg\/dL (o 30 mg\/L) y\/o VSG \u2265 40 mm\/h.<\/li><li><strong>Requiere \u2265 3 criterios de laboratorio de apoyo:<\/strong><\/li><\/ol><ul><li>Anemia normoc\u00edtica normocr\u00f3mica para la edad.<\/li><li>Plaquetas &gt; 450.000\/\u00b5L (despu\u00e9s del d\u00eda 7 de evoluci\u00f3n).<\/li><li>Leucocitosis global \u2265 15.000\/\u00b5L o neutrofilia.<\/li><li>Hipoalbuminemia \u2264 3,0 g\/dL.<\/li><li>Elevaci\u00f3n de ALT\/AST &gt; 40 U\/L.<\/li><li>Leucocituria est\u00e9ril \u2265 10 leucocitos\/campo en orina.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493594\" id=\"e-n-tab-content-1298493594\" data-tab-index=\"4\" style=\"--n-tabs-title-order: 4;\" class=\" elementor-element elementor-element-3a2304e e-flex e-con-boxed e-con e-child\" data-id=\"3a2304e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-488f5f9 e-con-full e-flex e-con e-child\" data-id=\"488f5f9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a65d222 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"a65d222\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>D. Diagn\u00f3stico diferencial sist\u00e9mico<\/b><\/span><\/p><ul><li><strong>Dengue \/ Arbovirosis:<\/strong> Fiebre alta bif\u00e1sica, mialgias intensas, exantema en \u00abislas blancas en mar rojo\u00bb, trombocitopenia temprana, leucopenia. Apoyo: Hematolog\u00eda (hemoconcentraci\u00f3n), prueba NS1 \/ Serolog\u00eda IgM espec\u00edfica.<\/li><li><strong>Escarlatina (Streptococcus pyogenes):<\/strong> Exantema micropapular en papel de lija, l\u00edneas de Pastia, faringoamigdalitis purulenta exudativa. Responde a penicilina. Apoyo: Hisopado far\u00edngeo para test r\u00e1pido o cultivo, t\u00edtulos de ASTO.<\/li><li><strong>PIMS-TS \/ SIM-C (Post-COVID-19):<\/strong> Afectaci\u00f3n multiorg\u00e1nica severa, shock cardiog\u00e9nico temprano, elevaci\u00f3n desproporcionada de troponinas, pro-BNP y d\u00edmero D. Apoyo: Ferritina s\u00e9rica, d\u00edmero D, troponina I, ecocardiograma con severo da\u00f1o contr\u00e1ctil.<\/li><li><strong>Artritis Idiop\u00e1tica Juvenil Sist\u00e9mica (sAIJ):<\/strong> Fiebre en agujas diaria que desciende a la normalidad, exantema evanescente asalmonado durante picos febriles, hepatoesplenomegalia. Apoyo: Ferritina marcadamente elevada (&gt; 1.000 ng\/mL), ausencia de respuesta a IGIV.<\/li><\/ul><p>\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493595\" id=\"e-n-tab-content-1298493595\" data-tab-index=\"5\" style=\"--n-tabs-title-order: 5;\" class=\" elementor-element elementor-element-4da5f77 e-flex e-con-boxed e-con e-child\" data-id=\"4da5f77\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-1189e49 e-con-full e-flex e-con e-child\" data-id=\"1189e49\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-05c91e1 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"05c91e1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>E. Terapia farmacol\u00f3gica de primera l\u00ednea<\/b><\/span><\/p><ol><li><strong>Inmunoglobulina Humana Intravenosa (IGIV):<\/strong><\/li><\/ol><ul><li><strong>Dosis:<\/strong> 2 g\/kg de peso en infusi\u00f3n intravenosa \u00fanica (Nivel 1++, Grado A).<\/li><li><strong>Tiempo de infusi\u00f3n:<\/strong> 10 a 12 horas continuas con bomba de infusi\u00f3n.<\/li><li><strong>Monitorizaci\u00f3n:<\/strong> Control estricto de signos vitales cada 15-30 minutos en las dos primeras horas de infusi\u00f3n para prevenir reacciones anafilactoides o sobrecarga de volumen.<\/li><li><strong>Ventana terap\u00e9utica:<\/strong> M\u00e1xima eficacia dentro de los primeros 10 d\u00edas; si persiste fiebre pasados los 10 d\u00edas, debe administrarse igualmente.<\/li><li>2.\u00a0<strong>\u00c1cido Acetilsalic\u00edlico (AAS):<\/strong><\/li><\/ul><ul><li><strong>Fase antiinflamatoria (Aguda):<\/strong> 30 a 50 mg\/kg\/d\u00eda VO divididos en 4 dosis (cada 6 horas) (Nivel 1+, Grado A). Mantener hasta 48-72 horas tras cese febril.<\/li><li><strong>Fase antiagregante (Convalecencia):<\/strong> Reducir a 3 a 5 mg\/kg\/d\u00eda en dosis \u00fanica matutina (Nivel 1+, Grado A) por 6 a 8 semanas si no hay alteraciones coronarias.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493596\" id=\"e-n-tab-content-1298493596\" data-tab-index=\"6\" style=\"--n-tabs-title-order: 6;\" class=\" elementor-element elementor-element-9e4039e e-con-full e-flex e-con e-child\" data-id=\"9e4039e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-ca8d5a6 e-con-full e-flex e-con e-child\" data-id=\"ca8d5a6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1bebb5c elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"1bebb5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>F. Manejo de la enfermedad de kawasaki refractaria (10% a 20%)<\/b><\/span><\/p><p><strong>Definici\u00f3n:<\/strong> Persistencia o reaparici\u00f3n de fiebre (temperatura axilar \u2265 38,0 \u00b0C) entre las 36 horas y 7 d\u00edas posteriores a culminar la primera dosis de IGIV.<\/p><p>\u00a0<\/p><ul><li><strong>Opci\u00f3n A (Segunda Infusi\u00f3n de IGIV):<\/strong> 2 g\/kg en infusi\u00f3n \u00fanica de 10 a 12 horas (Nivel 2++, Grado B).<\/li><li><strong>Opci\u00f3n B (Pulsos de Corticoides):<\/strong> Metilprednisolona endovenosa a 30 mg\/kg\/d\u00eda (m\u00e1ximo 1 g\/d\u00eda) administrada en 2 a 3 horas durante 3 d\u00edas consecutivos, seguida de prednisona oral en desescalamiento (Nivel 2++, Grado B).<\/li><li><strong>Terapia Biol\u00f3gica (Casos resistentes a 2\u00aa l\u00ednea):<\/strong> Infliximab a 5 mg\/kg en infusi\u00f3n endovenosa lenta de 2 horas (Nivel 2+, Grado C).<\/li><\/ul><p>\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493597\" id=\"e-n-tab-content-1298493597\" data-tab-index=\"7\" style=\"--n-tabs-title-order: 7;\" class=\" elementor-element elementor-element-1194ae4 e-flex e-con-boxed e-con e-child\" data-id=\"1194ae4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-57a3497 e-con-full e-flex e-con e-child\" data-id=\"57a3497\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-61a02ba elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"61a02ba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>G. Fase convaleciente, monitoreo ecocardiogr\u00e1fico y egreso <\/b><\/span><\/p><ul><li>Monitoreo ecocardiogr\u00e1fico transtor\u00e1cico obligatorio: Evaluaci\u00f3n basal al diagn\u00f3stico, a las 2 semanas y a las 6-8 semanas.<\/li><li>Pacientes con Z-score &lt; 2,0 y normalizaci\u00f3n de reactantes pueden suspender el AAS a las 6-8 semanas.<\/li><li>Todo egreso hospitalario debe consignar el nivel de riesgo cardiol\u00f3gico en la epicrisis m\u00e9dica.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493598\" id=\"e-n-tab-content-1298493598\" data-tab-index=\"8\" style=\"--n-tabs-title-order: 8;\" class=\" elementor-element elementor-element-c60dcca e-flex e-con-boxed e-con e-child\" data-id=\"c60dcca\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-7f04a34 e-con-full e-flex e-con e-child\" data-id=\"7f04a34\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6203d4d elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"6203d4d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>H. Disponibilidad farmac\u00e9utica y red de referencia en Venezuela<\/b><\/span><\/p><p><strong>Disponibilidad Farmacol\u00f3gica:<\/strong><\/p><ul><li><strong>IGIV<\/strong> (Flebogamma\u00ae, Privigen\u00ae, Octagam\u00ae, Intraglobin\u00ae; viales de 2.5 g, 5 g, 10 g): Fundaci\u00f3n BADAN Nacional (Los Cortijos, Caracas y sucursales regionales); IVSS (Farmacia de Alto Costo, Los Ruices y regiones).<\/li><li><strong>\u00c1cido Acetilsalic\u00edlico<\/strong> (Aspirina\u00ae, Coraspirina\u00ae, Cardipirina\u00ae, Ecotrin\u00ae; 81, 100 y 500 mg): Amplia disponibilidad en farmacias comunitarias.<\/li><li><strong>Metilprednisolona<\/strong> (Solu-Medrol\u00ae, Cryometasona\u00ae; viales 40 mg, 125 mg, 500 mg, 1 g): Farmacias hospitalarias, BADAN y red comercial.<\/li><li><strong>Infliximab<\/strong> (Remicade\u00ae, Remsima\u00ae; frasco ampolla 100 mg): Programa de Medicamentos de Alto Costo del IVSS y Fundaci\u00f3n BADAN.<\/li><\/ul><p>\u00a0<\/p><p><strong>Centros Hospitalarios de Referencia Cardiol\u00f3gica Pedi\u00e1trica:<\/strong><\/p><p>\u00a0<\/p><ul><li><strong>Regi\u00f3n Capital y Central:<\/strong> Hospital Cardiol\u00f3gico Infantil Latinoamericano \u00abDr. Gilberto Rodr\u00edguez Ochoa\u00bb (Caracas), Hospital de Ni\u00f1os \u00abJ.M. de los R\u00edos\u00bb (Caracas), Hospital Universitario de Caracas (HUC), Hospital de Ni\u00f1os \u00abDr. Jorge Lizarraga\u00bb (Valencia).<\/li><li><strong>Regiones Occidente, Oriente y Guayana:<\/strong> Hospital de Especialidades Pedi\u00e1tricas \/ SAHUM (Maracaibo), Hospital Pedi\u00e1trico \u00abDr. Agust\u00edn Zubillaga\u00bb (Barquisimeto), Hospital \u00abDr. Rafael Tob\u00edas Guevara\u00bb (Barcelona), Hospital \u00abDr. Ra\u00fal Leoni\u00bb (San F\u00e9lix).<\/li><li><strong>Angio-TC Coronario:<\/strong> Indicado ante aneurismas gigantes (Z-score \u2265 10 o &gt; 8 mm) o ventana ecocardiogr\u00e1fica insuficiente (Nivel 2++, Grado B).<\/li><\/ul><p>.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-1298493599\" id=\"e-n-tab-content-1298493599\" data-tab-index=\"9\" style=\"--n-tabs-title-order: 9;\" class=\" elementor-element elementor-element-7bd1aee e-flex e-con-boxed e-con e-child\" data-id=\"7bd1aee\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-e692cc2 e-con-full e-flex e-con e-child\" data-id=\"e692cc2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bb245f6 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"bb245f6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>I. Estratificaci\u00f3n longitudinal del riesgo coronario (Z-Score)<\/b><\/span><\/p><p><a href=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EstratificacionLongitudinalDelRiesgoCoronario.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-3013 size-large\" src=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EstratificacionLongitudinalDelRiesgoCoronario-1024x614.jpg\" alt=\"\" width=\"1024\" height=\"614\" srcset=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EstratificacionLongitudinalDelRiesgoCoronario-1024x614.jpg 1024w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EstratificacionLongitudinalDelRiesgoCoronario-300x180.jpg 300w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EstratificacionLongitudinalDelRiesgoCoronario-768x461.jpg 768w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EstratificacionLongitudinalDelRiesgoCoronario-1536x922.jpg 1536w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/EstratificacionLongitudinalDelRiesgoCoronario.jpg 2000w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-12984935910\" id=\"e-n-tab-content-12984935910\" data-tab-index=\"10\" style=\"--n-tabs-title-order: 10;\" class=\" elementor-element elementor-element-1776ea1 e-flex e-con-boxed e-con e-child\" data-id=\"1776ea1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-aa921e9 e-con-full e-flex e-con e-child\" data-id=\"aa921e9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9b500dd elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"9b500dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>J. Recomendaciones cl\u00ednicas, interacciones y transici\u00f3n\u00a0<\/b><\/span><\/p><ul><li><strong>Riesgo de S\u00edndrome de Reye:<\/strong> Todo paciente en pauta prolongada con AAS debe recibir vacunaci\u00f3n antigripal anual (inactivada) desde los 6 meses de edad. Ante influenza o varicela activa, rotar transitoriamente a dipiridamol o clopidogrel.<\/li><li><strong>Interacci\u00f3n con Ibuprofeno:<\/strong> El ibuprofeno compite con el AAS en la COX-1 plaquetaria y anula el efecto antiagregante. Contraindicado en concomitancia. Utilizar acetaminof\u00e9n\/paracetamol.<\/li><li><strong>Regla de los 11 Meses para Vacunas:<\/strong> La administraci\u00f3n de IGIV exige diferir por 11 meses la aplicaci\u00f3n de vacunas de virus vivos atenuados (SRP y Varicela) para evitar interferencia inmunol\u00f3gica.<\/li><li><strong>Transici\u00f3n al Adulto:<\/strong> Los pacientes con anomal\u00edas coronarias persistentes (Niveles III a V) requieren transferencia estructurada a cardiolog\u00eda de adultos con resumen cl\u00ednico exhaustivo.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-12984935911\" id=\"e-n-tab-content-12984935911\" data-tab-index=\"11\" style=\"--n-tabs-title-order: 11;\" class=\" elementor-element elementor-element-bcee6a4 e-flex e-con-boxed e-con e-child\" data-id=\"bcee6a4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-3eb45df e-con-full e-flex e-con e-child\" data-id=\"3eb45df\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-62c08e1 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"62c08e1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>K. Gu\u00eda y cuaderno de cuidado para padres y cuidadores<\/b><\/span><\/p><ul><li><strong>Qu\u00e9 es la enfermedad:<\/strong> Inflamaci\u00f3n no contagiosa de vasos sangu\u00edneos; no se transmite a otros ni\u00f1os y la mayor\u00eda se recupera por completo con el tratamiento precoz.<\/li><li><strong>Toma de la aspirina:<\/strong> No suspenderla por cuenta propia; dar a la misma hora con alimentos. Si vomita en los primeros 15 minutos, repetir la dosis. La descamaci\u00f3n de piel en manos y pies en semanas posteriores es normal e indolora.<\/li><li><strong>Escuela y deportes:<\/strong> Reintegro escolar al ceder la fiebre y recuperar el apetito. Sin restricciones deportivas si las coronarias est\u00e1n sanas; en caso de aneurismas, seguir las pautas del cardi\u00f3logo.<\/li><li><strong>Signos de alarma para acudir a urgencias de inmediato:<\/strong> Reaparici\u00f3n de fiebre \u2265 38 \u00b0C, dolor tor\u00e1cico o llanto inconsolable, palidez o fatiga marcada, v\u00f3mitos reiterados o dolor abdominal agudo, hematomas o sangrados anormales, o contacto con lechina (varicela) o gripe.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-12984935912\" id=\"e-n-tab-content-12984935912\" data-tab-index=\"12\" style=\"--n-tabs-title-order: 12;\" class=\" elementor-element elementor-element-8b36c6c e-flex e-con-boxed e-con e-child\" data-id=\"8b36c6c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-c0ae25c e-con-full e-flex e-con e-child\" data-id=\"c0ae25c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4fdd943 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"4fdd943\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>Resumen ejecutivo y fisiolog\u00eda vascular<\/b><\/span><\/p><p>La enfermedad de Kawasaki (EK) es una vasculitis necrotizante sist\u00e9mica aguda mediada inmunol\u00f3gicamente que lesiona predominantemente arterias de mediano calibre, con marcado tropismo sobre el \u00e1rbol coronario. Afecta principalmente a menores de 5 a\u00f1os y representa la causa primaria de cardiopat\u00eda adquirida en ni\u00f1os a escala global. El proceso patog\u00e9nico inicia con una respuesta inmunitaria innata y adaptativa hiperreactiva frente a ant\u00edgenos ambientales o infecciosos en pacientes gen\u00e9ticamente predispuestos, desencadenando infiltraci\u00f3n masiva de neutr\u00f3filos y linfocitos T en la \u00edntima y adventicia de los vasos. Dicha cascada inflamatoria provoca la destrucci\u00f3n progresiva de la l\u00e1mina el\u00e1stica interna, debilitamiento de la pared vascular y la consiguiente formaci\u00f3n de ectasias y aneurismas arteriales coronarios (AAC) en hasta el 25% de los pacientes no tratados oportunamente.<\/p><p>\u00a0<\/p><p>La administraci\u00f3n inmediata de Inmunoglobulina Humana Intravenosa (IGIV) a dosis de 2 g\/kg en infusi\u00f3n continua junto con \u00c1cido Acetilsalic\u00edlico (AAS) antes del d\u00e9cimo d\u00eda de evoluci\u00f3n febril abate la tasa de dilataciones y aneurismas a menos del 4%.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-12984935913\" id=\"e-n-tab-content-12984935913\" data-tab-index=\"13\" style=\"--n-tabs-title-order: 13;\" class=\" elementor-element elementor-element-96c57fb e-flex e-con-boxed e-con e-child\" data-id=\"96c57fb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-e0b9b83 e-con-full e-flex e-con e-child\" data-id=\"e0b9b83\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2fcd0b0 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"2fcd0b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><b>Lista de abreviaturas<\/b><\/span><\/p><ul><li><strong>AAC:<\/strong> Aneurismas Arteriales Coronarios<\/li><li><strong>AAS:<\/strong> \u00c1cido Acetilsalic\u00edlico<\/li><li><strong>ALT \/ AST:<\/strong> Alanina Aminotransferasa \/ Aspartato Aminotransferasa<\/li><li><strong>Angio-TC:<\/strong> Angiotomograf\u00eda Computarizada<\/li><li><strong>ECA:<\/strong> Ensayo Cl\u00ednico Aleatorizado<\/li><li><strong>EK:<\/strong> Enfermedad de Kawasaki<\/li><li><strong>HBPM:<\/strong> Heparina de Bajo Peso Molecular<\/li><li><strong>IGIV:<\/strong> Inmunoglobulina Humana Intravenosa<\/li><li><strong>IVSS:<\/strong> Instituto Venezolano de los Seguros Sociales<\/li><li><strong>PCR:<\/strong> Prote\u00edna C Reactiva<\/li><li><strong>PIMS-TS \/ SIM-C:<\/strong> S\u00edndrome Inflamatorio Multisist\u00e9mico Pedi\u00e1trico<\/li><li><strong>RS:<\/strong> Revisi\u00f3n Sistem\u00e1tica<\/li><li><strong>sAIJ:<\/strong> Artritis Idiop\u00e1tica Juvenil Sist\u00e9mica<\/li><li><strong>SRP:<\/strong> Sarampi\u00f3n, Rub\u00e9ola y Parotiditis<\/li><li><strong>SVPP:<\/strong> Sociedad Venezolana de Puericultura y Pediatr\u00eda<\/li><li><strong>UCIP:<\/strong> Unidad de Cuidados Intensivos Pedi\u00e1tricos<\/li><li><strong>VSG:<\/strong> Velocidad de Sedimentaci\u00f3n Globular<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-12984935914\" id=\"e-n-tab-content-12984935914\" data-tab-index=\"14\" style=\"--n-tabs-title-order: 14;\" class=\" elementor-element elementor-element-7744458 e-con-full e-grid e-con e-child\" data-id=\"7744458\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-bcf62f0 e-con-full e-flex e-con e-child\" data-id=\"bcf62f0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-04705ba e-con-full e-flex e-con e-child\" data-id=\"04705ba\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ba7cde8 elementor-widget elementor-widget-text-editor\" data-id=\"ba7cde8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><strong>Autores<\/strong><\/span><\/p>\n<p><strong>Pauta estandarizada basada en la evidencia adaptada a la pr\u00e1ctica pedi\u00e1trica venezolana<\/strong><br><strong>Autor Principal:<\/strong> Dr. Fidel Ernesto Echeverr\u00eda Nava (Pediatra &#8211; Cardi\u00f3logo Infantil)<\/p><p><strong>Correo electr\u00f3nico:<\/strong> fidel.cardiologia@gmail.com<\/p><p><strong>Fecha de Elaboraci\u00f3n:<\/strong> Octubre 2026 | C\u00f3digo: SVPP-GC-CV-2026-04<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-12984935915\" id=\"e-n-tab-content-12984935915\" data-tab-index=\"15\" style=\"--n-tabs-title-order: 15;\" class=\" elementor-element elementor-element-e6b7f31 e-con-full e-grid e-con e-child\" data-id=\"e6b7f31\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-7247702 e-con-full e-flex e-con e-child\" data-id=\"7247702\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-9390\" class=\"elementor-element elementor-element-0093fc9 e-con-full e-flex e-con e-child\" data-id=\"0093fc9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7d5e26c elementor-widget elementor-widget-text-editor\" data-id=\"7d5e26c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #338fff;\"><strong>BIBLIOGRAF\u00cdA<\/strong><\/span><\/p><ol><li>McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, et al. Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association. Circulation. 2017;135(17):e927-e999.<\/li><li>Hamada H, Suzuki H, Onouchi Y, Ebata R, Terai M. Clinical practice guideline for Kawasaki disease: 2020 update. Pediatr Int. 2022;64(1):e15011.<\/li><li>Gorelik M, Chung SA, Ardalan K, Binstadt BA, Fallon L, Fuhlbrigge RC, et al. 2021 American College of Rheumatology\/Vasculitis Foundation Guideline for the Management of Kawasaki Disease. Arthritis Care Res (Hoboken). 2022;74(4):538-548.<\/li><li>de Graeff N, Groot N, Ozen S, Eleftheriou D, Avcin T, Bader-Meunier B, et al. European consensus-based recommendations for the diagnosis and treatment of rare paediatric vasculitides &#8211; the SHARE initiative. Rheumatology (Oxford). 2019;58(4):656-671.<\/li><li>Kobayashi T, Ayusawa M, Suzuki H, Abe J, Ito S, Kato T, et al. Revision of diagnostic guidelines for Kawasaki disease (the 6th revised edition). Pediatr Int. 2020;62(10):1135-1138.<\/li><li>Barrios T, Cardozo MA, L\u00f3pez M. Manejo cl\u00ednico de las vasculitis pedi\u00e1tricas: Recomendaciones y adaptaciones locales en Venezuela. Arch Venez Pueric Pediatr. 2023;86(2):45-52.<\/li><li>Rife E, Gedalia A. Kawasaki Disease: An Update. Curr Rheumatol Rep. 2020;22(10):75.<\/li><li>Sociedad Venezolana de Puericultura y Pediatr\u00eda. Pautas terap\u00e9uticas en patolog\u00eda cardiovascular pedi\u00e1trica y uso racional de hemoderivados. Arch Venez Pueric Pediatr. 2024;87(1):12-20.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region tabpanel\" aria-labelledby=\"e-n-accordion-item-9390 e-n-tab-title-12984935916\" id=\"e-n-tab-content-12984935916\" data-tab-index=\"16\" style=\"--n-tabs-title-order: 16;\" class=\" elementor-element elementor-element-389ed88 e-flex e-con-boxed e-con e-child\" data-id=\"389ed88\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2503971 elementor-widget elementor-widget-text-editor\" data-id=\"2503971\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-845 aligncenter\" src=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/PDF_file_icon.svg_-244x300.png\" alt=\"\" width=\"52\" height=\"64\" srcset=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/PDF_file_icon.svg_-244x300.png 244w, https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/PDF_file_icon.svg_.png 400w\" sizes=\"(max-width: 52px) 100vw, 52px\" \/><a href=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2026\/10\/Guia-Clinica-SVPP-Enfermedad-de-Kawasaki-2.pdf\">Gu\u00eda Cl\u00ednica Diagn\u00f3stico, manejo y tratamiento de la enfermedad de Kawasaki<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d45fa8b e-grid e-con-boxed e-con e-parent\" data-id=\"d45fa8b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8fe0415 e-grid e-con-full e-con e-child\" data-id=\"8fe0415\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-e6dfe62 e-grid e-con-full e-con e-child\" data-id=\"e6dfe62\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ba6e1a8 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"ba6e1a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm elementor-animation-push\" href=\"https:\/\/videoteca.svpediatria.org\/wp-content\/uploads\/2025\/09\/Proyecto-Guias-Medicas.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-book-medical\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M448 358.4V25.6c0-16-9.6-25.6-25.6-25.6H96C41.6 0 0 41.6 0 96v320c0 54.4 41.6 96 96 96h326.4c12.8 0 25.6-9.6 25.6-25.6v-16q0-9.6-9.6-19.2c-3.2-16-3.2-60.8 0-73.6q9.6-4.8 9.6-19.2zM144 168a8 8 0 0 1 8-8h56v-56a8 8 0 0 1 8-8h48a8 8 0 0 1 8 8v56h56a8 8 0 0 1 8 8v48a8 8 0 0 1-8 8h-56v56a8 8 0 0 1-8 8h-48a8 8 0 0 1-8-8v-56h-56a8 8 0 0 1-8-8zm236.8 280H96c-19.2 0-32-12.8-32-32s16-32 32-32h284.8z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Proyecto Gu\u00edas Cl\u00ednicas<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b929b99 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"b929b99\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm elementor-animation-push\" href=\"https:\/\/www.svpediatria.org\/secciones\/comunidad\/articulos-para-la-familia\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-users\" viewBox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M96 224c35.3 0 64-28.7 64-64s-28.7-64-64-64-64 28.7-64 64 28.7 64 64 64zm448 0c35.3 0 64-28.7 64-64s-28.7-64-64-64-64 28.7-64 64 28.7 64 64 64zm32 32h-64c-17.6 0-33.5 7.1-45.1 18.6 40.3 22.1 68.9 62 75.1 109.4h66c17.7 0 32-14.3 32-32v-32c0-35.3-28.7-64-64-64zm-256 0c61.9 0 112-50.1 112-112S381.9 32 320 32 208 82.1 208 144s50.1 112 112 112zm76.8 32h-8.3c-20.8 10-43.9 16-68.5 16s-47.6-6-68.5-16h-8.3C179.6 288 128 339.6 128 403.2V432c0 26.5 21.5 48 48 48h288c26.5 0 48-21.5 48-48v-28.8c0-63.6-51.6-115.2-115.2-115.2zm-223.7-13.4C161.5 263.1 145.6 256 128 256H64c-35.3 0-64 28.7-64 64v32c0 17.7 14.3 32 32 32h65.9c6.3-47.4 34.9-87.3 75.2-109.4z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Padres de Familia<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc275e7 e-grid e-con-boxed e-con e-parent\" data-id=\"cc275e7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-bea77e1 e-con-full e-flex e-con e-child\" data-id=\"bea77e1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-87563f5 e-con-full e-flex e-con e-child\" data-id=\"87563f5\" 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